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GeneBe

MCP server · hosted · v0.1.0 · net.genebe/genebe-mcp
Online · tested 41m agoNEW · 2h agoSeen in the registry 1h ago

Annotate and classify human genetic variants with GeneBe (ACMG, gnomAD, ClinVar). Research use only.

Website ↗Source code ↗How to connect ↓

What it does

GeneBe is an MCP server, a connector that lets an AI assistant use it as a tool. It is hosted: an assistant connects to it over the internet, nothing to install.

No capability identified yet from its description.

Facts come from the Official MCP Registry, as declared by the publisher. Capabilities are matched automatically (low confidence) and are not a test of the tool.

At a glance

Hosted (remote)YES
Local installNO
Version0.1.0
PriceNot in the registry
First seen22 Oct 2026
Last checked1h ago

How to connect

As declared in the Official MCP Registry · hosted endpoint tested by Electra Index 41m ago (live check)

Hosted endpoint

  • https://mcp.genebe.net/v1/mcp streamable-http

In Claude Code: claude mcp add --transport http genebe https://mcp.genebe.net/v1/mcp

MCP settings (Claude Desktop, Cursor and other MCP clients)

{
  "mcpServers": {
    "genebe": {
      "url": "https://mcp.genebe.net/v1/mcp"
    }
  }
}

Live check

Electra Index connected to the hosted endpoint 41m ago

ONLINE GeneBe answered an MCP connection on 22 Oct 2026 and introduced itself as GeneBe 0.1.0 (MCP protocol 2025-06-18).

6 tools offered to AI assistants

  • annotate_variant · Annotate and classify one human genetic variant using GeneBe. Start here for any question about a variant (what is it, is it pathogenic/benign, how common is it). Returns the ACMG verdict with points and criteria, population frequency (gnom
  • explain_acmg_decision_path · Explain step by step why each classification criterion did or did not apply to a variant. Use after annotate_variant when the user asks "why was this classified that way?". Returns an ASCII rendering of the decision tree with the evaluated
  • convert_variant · Convert a variant written in any notation into normalized hg38 genomic coordinates. Use when you only need the chr/pos/ref/alt of a variant (for example to translate HGVS or an rsID), without annotation. Does not classify the variant; use a
  • get_variant_effects · List a variant's predicted molecular consequences on every overlapping transcript. Returns per-transcript HGVS (c. and p.), consequence terms (e.g. missense_variant) and impact, most severe and MANE Select transcripts first. Lightweight: no
  • get_gene · Look up a human gene: identifiers, location, MANE Select transcript, ClinGen gene-disease validity. Use for questions about a gene rather than a specific variant. Transcripts are listed with MANE Select first and capped; check total_transcr
  • liftover_coordinate · Convert a genomic position, interval or variant between genome builds (hg19, hg38, t2t). Check `status`: RESOLVED means one result, AMBIGUOUS means several candidates, anything else means it could not be mapped (see errors). For variants, r

What "online" means: the server answered an MCP connection at the time of the check. It is not a guarantee of security, quality or continuous uptime. How we test: we open an MCP session and ask for the tool list, as an AI assistant would. We never run a tool and never send a key. Checked every few days. Method

Is this your server? Monitoring Pro: a check every 30 minutes and an email within the hour when it stops answering. $9.99/month.

Facts & evidence

Each fact shows where it was seen and when.
FactValueEvidenceSourceLast confirmed
Hosted endpointhttps://mcp.genebe.net/v1/mcpDECLAREDSRC-001 Official MCP Registry1h ago
Local install (package)noDECLAREDSRC-001 Official MCP Registry1h ago
Remote access (hosted)yesDECLAREDSRC-001 Official MCP Registry1h ago
Websitehttps://genebe.netDECLAREDSRC-001 Official MCP Registry1h ago
Repositoryhttps://github.com/genebe-net/genebe-mcpDECLAREDSRC-001 Official MCP Registry1h ago
Registry statusactiveDECLAREDSRC-001 Official MCP Registry1h ago
Version0.1.0DECLAREDSRC-001 Official MCP Registry1h ago
MCP serveryesDECLAREDSRC-001 Official MCP Registry1h ago

Change history

  • NEW22 Oct 2026
    first seen in the index

Is this page accurate?

Flag it and our robot re-checks the official source. Reports never change a score.

Questions about GeneBe

How do I connect GeneBe?

Use the hosted endpoint https://mcp.genebe.net/v1/mcp in your assistant's MCP settings. The exact settings are in "How to connect" above, as declared in the Official MCP Registry.

What tools does GeneBe offer?

When Electra Index connected on 22 Oct 2026, it listed 6 tools: annotate_variant, explain_acmg_decision_path, convert_variant, get_variant_effects, get_gene, liftover_coordinate. The full list is in "Live check" above.

Is GeneBe online?

Yes. Its hosted endpoint answered an MCP connection from Electra Index 41m ago.